string strings = “4,6,8\n9,4”;
string [] split = strings .Split(new Char [] {‘,’ , ‘\n’ });

string [] split = strings .Split(new Char [] {‘,’ , ‘\n’ }, StringSplitOptions.RemoveEmptyEntries);

string [] split = strings.Split(new Char[] { ‘,’, ‘\\’, ‘\n’ }, StringSplitOptions.RemoveEmptyEntries);

var s = “4,6,8\n9,4”;
var split = s.Split(new char[]{‘,’, ‘\n’});

using System.Text.RegularExpressions;
var i = “4,6,8 , 9\n\n4″;
var o = Regex.Split(i, @”[,\s\n]+”);